21st-century American actresses

Tané M. McClure (born June 8, 1958), sometimes credited as Tahnee Cain and Tané Cain, is an American actress, singer, producer, writer, director and film editor.

Vonetta Lawrence McGee (January 14, 1945 – July 9, 2010) was an American actress. She debuted in the Spaghetti Western The Great Silence and went on to appear in blaxploitation films such as Hammer, Melinda, Blacula, Shaft in Africa, Detroit 9000, and 1974's Thomasine & Bushrod alongside her then-boyfriend Max Julien. In 1975, she was Clint Eastwood's co-star in The Eiger Sanction. She was a regular on the 1987 Universal Television situation comedy Bustin' Loose, starring as Mimi Shaw for its only season (1987–88).

Leigh-Allyn Baker (born March 13, 1972) is an American actress. She had recurring roles on Charmed and as Ellen on Will & Grace, and a starring role as mother Amy Duncan on the Disney Channel sitcom Good Luck Charlie. She also provided the voice of Abby on the computer-animated Nickelodeon series Back at the Barnyard.

Betsy Drake (September 11, 1923 – October 27, 2015) was an American actress, writer and psychotherapist. She was the third wife of actor Cary Grant.

America Athene Olivo (born January 5, 1978) is an American actress and singer best known as a member of the band Soluna, for her roles in the films Bitch Slap (2009), Friday the 13th (2009) and Maniac (2012), as well as starring in the Broadway musical Spider-Man: Turn Off the Dark.

Beau Jesse Garrett (born December 28, 1982) is an American actress and model. She began her career appearing in GUESS advertisements in the late 1990s after being discovered by an Elite modeling agent at age fourteen. She made her feature film debut in the horror film Turistas (2006) before portraying Captain Raye in Fantastic Four: Rise of the Silver Surfer (2007) and Gem in Tron: Legacy (2010).
Garrett would later appear as a regular guest star on the television series Criminal Minds: Suspect Behavior (2011) and had a regular role on Girlfriends' Guide to Divorce from 2014 to 2018. In 2017, she portrayed Jessica Preston on the ABC series The Good Doctor.

Erica Fawn Gimpel (born June 25, 1964) is an American actress, singer, dancer, and composer. She is best known for her roles on television shows Fame as Coco Hernandez and on Profiler as Angel Brown. She is also known for her recurring roles on the television shows ER as Adele Newman and on Veronica Mars as Alicia Fennel. From 2018 to 2020, Gimpel had a series regular role as Trish on the series God Friended Me.
Gimpel was a judge on RTÉ One's Fame: The Musical, an Irish TV talent show seeking a boy and a girl to play Nick and Serena respectively in the Irish touring production of Fame.In January 2010, Gimpel released her first CD, Spread your Wings and Fly.

Kellie Martin (born October 16, 1975) is an American actress. She is known for her roles as Rebecca "Becca" Thatcher in Life Goes On (1989–1993), Lucy Knight on ER (1998–2000), Samantha Kinsey in the Mystery Woman TV film series (2003–2007), and as Hailey Dean in the Hailey Dean Mystery TV film series (2016–2019).

Mitzi Kapture (born Mitzi Gaynor Donahue; May 2, 1962) is an American actress, known for her role as Sgt. Rita Lee Lance in the CBS/USA Network crime drama series Silk Stalkings from 1991 to 1995.

Alison Ann Sweeney (born September 19, 1976) is an American actress, reality show host, director and author. Sweeney is best known for her portrayal of Samantha "Sami" Brady on the NBC soap opera Days of Our Lives, a role she played under contract with the show from January 6, 1993 to October 30, 2014. In this role, she earned a Daytime Emmy Award nomination, four Soap Opera Digest Awards and a Fan Voted Daytime Emmy Award. After making sporadic appearances since then, she returned as a series regular in 2021. In 2007, she became the host of The Biggest Loser in its fourth season, and left the series at the end of the 16th season in 2015.