American people of Greek descent

George Economou (September 24, 1934 – May 3, 2019) was an American poet and translator.

Christy Peter Mihos (June 13, 1949 – March 25, 2017) was an American politician and businessman from Massachusetts. He was an Independent candidate for governor of Massachusetts in 2006. He ran for the Republican nomination for governor in 2010, but did not receive enough votes at the Republican Convention to qualify for the primary ballot.

Dean Karnazes (English: car-NEH-zis; born Constantinos Karnazes; August 23, 1962), is an American ultramarathon runner, and author of Ultramarathon Man: Confessions of an All-Night Runner, which details ultra endurance running for the general public.

Gregory David Massialas (born May 20, 1956) is an American foil fencer and fencing coach.