Rebecca Jeanne Riley (April 11, 2002 – December 13, 2006) was a four-year-old girl from Massachusetts. In December 2006, Riley's parents gave Riley—who had been diagnosed with attention-deficit hyperactivity disorder and pediatric bipolar disorder between two and three years old—a lethal dose of clonidine. Her death sparked significant controversy over diagnosis of psychiatric conditions and subsequent prescription of psychotropic medication in children.
Neil Entwistle (born 18 September 1978) is an English man convicted of murdering his American wife, Rachel, and their infant daughter, Lillian, on 20 January 2006, in Hopkinton, Massachusetts, United States. He was sentenced to life imprisonment without parole and is incarcerated at Old Colony Correctional Center in Bridgewater, Massachusetts.
Molly Anne Bish (August 2, 1983 – June 27, 2000) was a sixteen-year-old American girl from rural Worcester County, Massachusetts, who disappeared while working as a lifeguard in her hometown of Warren, Massachusetts. Her remains were found three years later in neighboring Hampden County after what became the largest search in the state's history. Police believe Bish was the victim of a homicide and several suspects have been publicly identified, but the case remains officially unresolved as of 2024.
Holly Kristen Piirainen (January 19, 1983 – August 5, 1993) was a 10-year-old American murder victim from Grafton, Massachusetts. She and her brother had been visiting their grandparents in Sturbridge, Massachusetts when Holly was murdered. Her murder remains unsolved.