American people of French descent

Paul Delos Boyer (July 31, 1918 – June 2, 2018) was an American biochemist, analytical chemist, and a professor of chemistry at University of California Los Angeles (UCLA). He shared the 1997 Nobel Prize in Chemistry for research on the "enzymatic mechanism underlying the biosynthesis of adenosine triphosphate (ATP)" (ATP synthase) with John E. Walker, making Boyer the first Utah-born Nobel laureate; the remainder of the Prize in that year was awarded to Danish chemist Jens Christian Skou for his discovery of the Na+/K+-ATPase.

Anne MacKaye Chapman (January 27, 1922 – June 12, 2010) was a Franco-American ethnologist who focused on the people of Mesoamerica writing several books, co-producing movies, and capturing sound recordings of rare languages from the Northern Triangle of Central America to Cape Horn in South America.

Robert Guestier Goelet (guh-LET; September 28, 1923 – October 9, 2019) was a prominent American philanthropist and former executive at Chemical Bank, founded by the Goelet family in 1824.

Anne St. Marie (June 16, 1926 – 1986) was an American fashion model, also known as Anne Sainte-Marie, and one of the leading models of the 1950s.

Mari Blanchard (born Mary E. Blanchard, April 13, 1923 – May 10, 1970) was an American film and television actress, known foremost for her roles as a B movie femme fatale in American productions of the 1950s and early 1960s.

Olivier Knox is a French American journalist who is the chief Washington correspondent for Sirius XM. In addition to his career at Agence France-Presse and Yahoo News, he is most known for chairing the White House Correspondents' Association and for his reboot of the White House Correspondents Dinner into its original format, which saw the elimination of the tradition of having a comedian as the featured speaker and an absence of A-list celebrities at the event.

Myra Yvonne Chouteau () (March 7, 1929 – January 24, 2016) was an American ballerina and one of the "Five Moons" or Native prima ballerinas of Oklahoma. She was the only child of Corbett Edward and Lucy Annette Chouteau. She was born March 7, 1929, in Fort Worth, Texas. In 1943, she became the youngest dancer ever accepted to the Ballet Russe de Monte-Carlo, where she worked for fourteen years. In 1962, she and her husband, Miguel Terekhov, founded the first fully accredited university dance program in the United States, the School of Dance at the University of Oklahoma. A member of the Shawnee Tribe, she also had French ancestry, the great-great-great-granddaughter of Maj. Jean Pierre Chouteau. From the Chouteau family of St. Louis, he established Oklahoma's oldest European-American settlement at the present site of Salina in 1796. She grew up in Vinita, Oklahoma.

Jesse Eden Metcalfe (born December 9, 1978) is an American actor. He is known for his portrayal of John Rowland on Desperate Housewives. Metcalfe has also had notable roles on Passions and played the title role in John Tucker Must Die. He starred as Christopher Ewing in the TNT continuation of Dallas, based on the 1978 series of the same name. From 2016 to 2021, Metcalfe starred as Trace Riley in Hallmark Channel's hit series Chesapeake Shores.

Gervais Raoul Victor Lufbery (March 14, 1885 – May 19, 1918) was a French and American fighter pilot and flying ace in World War I. Because he served in both the French Air Force, and later the United States Army Air Service in World War I, he is sometimes listed alternately as a French ace or as an American ace. Officially, all but one of his 17 combat victories came while flying in French units.

Marie Adrien Persac (1823–1873) was a French-born American fine art painter, cartographer, photographer, and art teacher. Persac watercolored south Louisiana plantation houses and other aspects of the Southern landscape, and his work has much importance to Southern historians. His work was often signed, A. Persac.