California Institute of Technology faculty

Linus Carl Pauling ( PAW-ling; February 28, 1901 – August 19, 1994) was an American chemist, biochemist, chemical engineer, peace activist, author, and educator. He published more than 1,200 papers and books, of which about 850 dealt with scientific topics. New Scientist called him one of the 20 greatest scientists of all time. For his scientific work, Pauling was awarded the Nobel Prize in Chemistry in 1954. For his peace activism, he was awarded the Nobel Peace Prize in 1962. He is one of five people to have won more than one Nobel Prize (the others being Marie Curie, John Bardeen, Frederick Sanger, and Karl Barry Sharpless). Of these, he is the only person to have been awarded two unshared Nobel Prizes, and one of two people to be awarded Nobel Prizes in different fields, the other being Marie Curie.Pauling was one of the founders of the fields of quantum chemistry and molecular biology. His contributions to the theory of the chemical bond include the concept of orbital hybridisation and the first accurate scale of electronegativities of the elements. Pauling also worked on the structures of biological molecules, and showed the importance of the alpha helix and beta sheet in protein secondary structure. Pauling's approach combined methods and results from X-ray crystallography, molecular model building, and quantum chemistry. His discoveries inspired the work of Rosalind Franklin, James Watson, Francis Crick, and Maurice Wilkins on the structure of DNA, which in turn made it possible for geneticists to crack the DNA code of all organisms.In his later years, he promoted nuclear disarmament, as well as orthomolecular medicine, megavitamin therapy, and dietary supplements, especially ascorbic acid (commonly known as Vitamin C). None of his ideas concerning the medical usefulness of large doses of vitamins have gained much acceptance in the mainstream scientific community. He was married to the American human rights activist Ava Helen Pauling.

Milton Spinoza Plesset (7 February 1908 – 19 February 1991) was an American applied physicist who worked in the field of fluid mechanics and nuclear energy. He was elected to the National Academy of Engineering in 1979 for his fundamental contributions to multiphase flows, bubble dynamics, and safety of nuclear reactors. Plesset served as professor of engineering science at California Institute of Technology during 1951 to 1978. Notable scientists Andrea Prosperetti, Norman Zabusky, and Chris Whipple finished their doctoral work under Plesset's guidance. Milton Plesset, Andrea Prosperetti, and Chris Whipple were elected to the National Academy of Engineering.
He with Christian Møller are known for the Møller–Plesset perturbation theory.
The Rayleigh-Plesset equation describing the dynamics of a bubble in an infinite body of fluid is also named after him.

Roy Walter Gould (April 25, 1927 – February 19, 2022) was an American electrical engineer and physicist who specialized in plasma physics. In 1959, he (together with Alvin Trivelpiece) was the first to describe electrostatic waves that were propagating at the boundary of a magnetized plasma column, now commonly known as Trivelpiece–Gould modes.Gould was elected a member of the National Academy of Engineering in 1971 for pioneering contributions to microwave electronics and plasma physics and distinguished service in higher education.

Donald Delbert Clayton (March 18, 1935 – January 3, 2024) was an American astrophysicist whose most visible achievement was the prediction from nucleosynthesis theory that supernovae are intensely radioactive. That earned Clayton the NASA Exceptional Scientific Achievement Medal (1992) for “theoretical astrophysics related to the formation of (chemical) elements in the explosions of stars and to the observable products of these explosions”. Supernovae thereafter became the most important stellar events in astronomy owing to their profoundly radioactive nature. Not only did Clayton discover radioactive nucleosynthesis during explosive silicon burning in stars but he also predicted a new type of astronomy based on it, namely the associated gamma-ray line radiation emitted by matter ejected from supernovae. That paper was selected as one of the fifty most influential papers in astronomy during the twentieth century for the Centennial Volume of the American Astronomical Society. He gathered support from influential astronomers and physicists for a new NASA budget item for a gamma-ray-observatory satellite, achieving successful funding for Compton Gamma Ray Observatory. With his focus on radioactive supernova gas Clayton discovered a new chemical pathway causing carbon dust to condense there by a process that is activated by the radioactivity.Clayton also authored a novel, The Joshua Factor (1985), a parable of the origin of mankind utilizing the mystery of solar neutrinos; a science autobiography and a memoir; and a history of the origin of each isotope, Handbook of Isotopes in the Cosmos (Cambridge Univ. Press, 2003).
Clayton died on January 3, 2024, at the age of 88.

Arie Jan Haagen-Smit (December 22, 1900 – March 17, 1977) was a Dutch chemist. He is best known for linking the smog in Southern California to automobiles and is therefore known by many as the "father" of air pollution control. After serving as an original board member of the Motor Vehicle Pollution Control Board, formed in 1960 to combat the smog, Dr. Haagen-Smit became the California Air Resources Board's first chairman in 1968. Shortly before his death in Pasadena, California, of lung cancer, the Air Resources Board's El Monte Laboratory was named after him.

Robert Benjamin Leighton (; September 10, 1919 – March 9, 1997) was a prominent American experimental physicist who spent his professional career at the California Institute of Technology (Caltech). His work over the years spanned solid state physics, cosmic ray physics, the beginnings of modern particle physics, solar physics, the planets, infrared astronomy, and millimeter- and submillimeter-wave astronomy. In the latter four fields, his pioneering work opened up entirely new areas of research that subsequently developed into vigorous scientific communities.

Gerald J. Wasserburg (March 25, 1927 – June 13, 2016) was an American geologist. At the time of his death, he was the John D. MacArthur Professor of Geology and Geophysics, emeritus, at the California Institute of Technology. He was known for his work in the fields of isotope geochemistry, cosmochemistry, meteoritics, and astrophysics.