Italian pathologists

Emilio_Veratti

Emilio Veratti (24 March 1872, Varese – 24 February 1967) was an Italian anatomist and pathologist. He is known for his discovery of the sarcoplasmic reticulum.
He studied medicine at the Universities of Pavia and Bologna, where he received his doctorate in 1896. Following graduation he worked for Camillo Golgi (1843-1926) at the Institute of General Pathology in Pavia. Here he distinguished himself by way of research in the fields of histology and microbiology. Eventually he attained the title of "libero docente" (equivalent of privat-docent) in histology and general pathology.
In 1921 he established a bacteriology laboratory in the medical clinic at Pavia. In 1930 he was successor to Aldo Perroncito (1882-1929) as professor of general pathology, a position he kept until his retirement in 1942.In March 1902, he provided the first accurate description of the reticular network (sarcoplasmic reticulum) in skeletal muscle fibers. His published findings attracted little attention at the time, and as years passed by, his discovery was all but forgotten. In 1961 "Veratti's reticulum" was re-discovered through the use of electron microscopy.

Aldo_Perroncito

Aldo Perroncito (18 May 1882, Turin – 1929) was an Italian pathologist. He was the son of parasitologist Edoardo Perroncito (1847–1936). He is known for research involving regeneration of peripheral nerves, kinetic behavior of the Golgi apparatus during mitosis, and studies of pellagra.
In 1905 he obtained his medical doctorate from the University of Pavia, where he spent the following five years as an assistant to pathologist Camillo Golgi (1846–1926). During this time period he also conducted studies at the Institute of Physiology in Berlin and at the Institute of Parasitology in Paris. Afterwards he taught classes in general pathology at the University of Cagliari, returning to Pavia in 1922 as a full professor and as a successor to Camillo Golgi.
While an assistant at Pavia, he demonstrated with a severed peripheral nerve, that the stump attached to the cell body was able to survive and regenerate new branches, while its other stump, being detached from the cell body, degenerated. In 1910 he discovered that a Golgi body dissociated into a number of elongated structures during cell division. Perroncito named the split up pieces "dictyosomes".

Adelchi_Negri

Adelchi Negri (16 July 1876 – 19 February 1912) was an Italian pathologist and microbiologist born in Perugia.
He studied medicine and surgery at the University of Pavia, where he was a pupil of Camillo Golgi (1843–1926). After graduation in 1900, he became an assistant to Golgi at his pathological institute. In 1909 Negri became a professor of bacteriology, and the first official instructor of bacteriology in Pavia. On 19 February 1912 he died of tuberculosis at age 35.
Negri performed extensive research in the fields of histology, hematology, cytology, protozoology and hygiene. In 1903 he discovered the eponymous Negri bodies, defined as cytoplasmatic inclusion bodies located in the Purkinje cells of the cerebellum in cases of rabies in animals and humans. He documented his findings in an article titled Contributo allo studio dell'eziologia della rabbia, published in the journal Bollettino della Società medico-chirurgica. At the time, Negri mistakenly described the pathological agent of rabies as a parasitic protozoa. A few months later, Paul Remlinger (1871–1964) at the Constantinople Imperial Bacteriology Institute correctly demonstrated that the aetiological agent of rabies was not a protozoan, but a filterable virus.
Negri went on, however, to demonstrate in 1906 that the smallpox vaccine, then known as "vaccine virus", or "variola vaccinae", was also a filterable virus. During the latter part of his career, he became interested in malaria and was at the forefront in efforts to eradicate it from Lombardy. In 1906 he married his colleague Lina Luzzani and six years later, at the age of thirty-five, died of tuberculosis.

Adolfo_Ferrata

Adolfo Ferrata (26 April 1880 in Brescia – 9 March 1946) was an Italian pathologist and hematologist.
In 1904 he earned his medical degree from the University of Parma, spending the following years performing scientific research in clinics at Parma, Berlin and Naples. From 1921 to 1924 he was a professor of special medical pathology at the Universities of Messina and Siena, afterwards serving as a professor of clinical medicine at the University of Pavia, a position he kept for the remainder of his career.Among his contributions to medical science are investigations on the structure and embryology of the kidney, research on the morphology of intestinal villi and haematopoietic studies in normal and pathological conditions. In his research of haematopoiesis, Ferrata helped demonstrate the systemic nature of leukemia, leading him to support an hypothesis that elements of the blood (erythrocytes, leukocytes, and blood platelets) all originate from the hemocytoblast, a direct descendant of a mesenchymal cell, which he referred to as an emoistioblasto (hemohistioblast).In 1907 he was the first scientist to show that the complement could be split into two components that were singularly inactive, only regaining their activity when reunited.In 1920 Ferrata founded the journal "Haematologica".