20th-century Puerto Rican physicians

Rafael López Nussa (22 February 1885 – 3 March 1943) was a Puerto Rican physician and public servant. In 1916 López Nussa performed the first heart surgery operation in Puerto Rico.

Luis Ernesto Ramos Yordán (February 5, 1915 – January 27, 2005) was a Puerto Rican physician, legislator, and President of the House of Representatives of Puerto Rico from 1973 to 1977.

José Leandro Montalvo Guenard (1885 – 1950) was a Puerto Rican physician, inventor, anthropologist and historian. He is known for his "Rectificaciones Históricas: El Descubrimiento de Boriquén", published by Editorial del Llano, in Ponce, Puerto Rico, in 1933.