People from Guayama

Víctor Manuel Blanco (March 10, 1918 – March 8, 2011) was a Puerto Rican astronomer who in 1959 discovered Blanco 1, a galactic cluster. Blanco was the second Director of the Cerro Tololo Inter-American Observatory in Chile, which had the largest telescope in the Southern Hemisphere at the time. In 1995, the 4-meter telescope was dedicated in his honor and named the Víctor M. Blanco Telescope; it is also known as the "Blanco 4m."

Gilda Galán (January 16, 1917 – June 21, 2009) was a Puerto Rican actress, comedian, writer, composer, scriptwriter and poet. The veteran actress, whose career spanned decades, enjoyed one of the longest careers in the history of the Puerto Rican entertainment industry.