American actors with disabilities

Roseanne Cherrie Barr (born November 3, 1952) is an American actress, comedian, writer, and producer. She began her career in stand-up comedy before gaining acclaim in the television sitcom Roseanne (1988–1997; 2018). She won an Emmy and a Golden Globe Award for Best Actress for her work on the show.
Barr became a stand-up comedian in 1980. In the late 1980s and early 1990s, she gained fame through her role in Roseanne and other performances. She sparked controversy when performing "The Star-Spangled Banner" at a nationally aired baseball game on July 25, 1990. After singing the anthem in what many perceived to be a deliberately disrespectful manner, she grabbed her groin and spat. This performance was met with condemnation from baseball fans and sportswriters, and was called "disgraceful" by then-President George H. W. Bush.Barr has been active and outspoken on political issues. She unsuccessfully sought the Green Party's nomination for president in 2012, losing to physician Jill Stein. Later nominated by the left-wing Peace and Freedom Party, Barr received nearly 70,000 votes for president in the 2012 presidential election. After Donald Trump announced his candidacy for president in 2015, Kelly Weill of The Daily Beast wrote that Barr "veered right" in her politics. After Roseanne was revived, Trump called her to congratulate her on her show's ratings and thank her for her support. She has frequently defended her support of Trump, and has been criticized for making personal attacks and promoting conspiracy theories and fake news.Roseanne was revived in 2018 on ABC. A ratings success, it was renewed for an additional season but was canceled after Barr made a tweet condemned as racist by many commentators. She referred to the tweet as a "bad joke". In 2022, she announced a comeback comedy special to be released on Fox Nation in 2023.

Eliza Patricia Dushku (; born December 30, 1980) is an American actress. She is best known for starring as Faith in the supernatural drama series Buffy the Vampire Slayer (1998–2003) and its spin-off series Angel (2000–2003). She also had lead roles in the Fox supernatural drama series Tru Calling (2003–2005) and the Fox science fiction series Dollhouse (2009–2010), for which she was a producer.Dushku had starring roles in various films, including True Lies (1994), Bye Bye Love (1995), Bring It On (2000), Jay and Silent Bob Strike Back (2001), The New Guy (2002), Wrong Turn (2003), On Broadway (2007), The Scribbler (2014), Jane Wants a Boyfriend (2015), and Eloise (2016). She has also done voice work for numerous video games and animated films.

Brad Williams (born January 13, 1984) is an American stand-up comedian and actor who has appeared in numerous films and television shows. He was born with achondroplasia.

Luigi Francis "Shorty" Rossi (born February 10, 1969) is the former star of Pit Boss, a reality series (now cancelled) on Animal Planet. He is also the owner and talent manager of Shortywood Productions, a company that works with little people in the entertainment industry and Shorty's Rescue, an organization set up for Pit Bull rescue (which is no longer in service).

Jamie Brewer is an American actress and model. She is best known for her roles in the FX horror anthology television series American Horror Story. In its first season, Murder House, she portrayed Adelaide "Addie" Langdon; in the third season, Coven, she portrayed Nan, an enigmatic and clairvoyant witch; in the fourth season Freak Show, she portrayed Chester Creb's vision of his doll, Marjorie; in the seventh season Cult, she portrayed Hedda, a member of the 'SCUM' crew, led by feminist Valerie Solanas; and she also returned to her role as Nan in the eighth season, Apocalypse.

Rene Kirby (born February 27, 1955) is an American film and television actor. He is perhaps best known for his performance in the Farrelly Brothers' film Shallow Hal. In this film he plays the role of Walt, a man who, like Kirby himself, was born with spina bifida.

August Clarence Swensen (December 29, 1917 – February 25, 2009) was an American actor and was one of the Munchkins in the 1939 film The Wizard of Oz.