Male actors from Massachusetts

Conan Christopher O'Brien (born April 18, 1963) is an American television host, comedian, writer, and producer. He is best known for having hosted late-night talk shows for almost 28 years, beginning with Late Night with Conan O'Brien (1993–2009) and The Tonight Show with Conan O'Brien (2009–2010) on the NBC television network, and Conan (2010–2021) on the cable channel TBS. Before his hosting career, O'Brien was a writer for the NBC sketch comedy series Saturday Night Live from 1988 to 1991, and the Fox animated sitcom The Simpsons from 1991 to 1993. He has also been host of the podcast series Conan O'Brien Needs a Friend since 2018 and is set to launch a travel show, Conan O'Brien Must Go, on Max.
Born in Brookline, Massachusetts, O'Brien was raised in an Irish Catholic family. He served as president of The Harvard Lampoon while attending Harvard University, and was a writer for the sketch comedy series Not Necessarily the News. After writing for several comedy shows in Los Angeles, he joined the writing staff of Saturday Night Live. O'Brien was a writer and producer for The Simpsons for two seasons until he was selected by Lorne Michaels and NBC to take over David Letterman's position as host of Late Night in 1993. Despite unfavorable reviews and threats of cancellation in the show's first years, O'Brien and the show developed and became highly regarded, earning a Primetime Emmy Award for Outstanding Writing for a Variety Series. He hosted Late Night for 16 years, and as of 2023 is still the longest-serving host in the history of the franchise.
In 2009, O'Brien moved from New York to Los Angeles to host his own incarnation of The Tonight Show for seven months until highly publicized network politics prompted a host change in 2010. After this departure, O'Brien hosted a 32-city live comedy tour titled The Legally Prohibited from Being Funny on Television Tour, which was the subject of the documentary Conan O'Brien Can't Stop (2011). He then hosted Conan from 2010 to 2021. Throughout his career, he has also hosted a number of awards shows and television specials, including the Emmy Awards in 2002 and 2006 and the White House Correspondents' dinner in 1995 and 2013. Conan was named one of Time's 100 Most Influential People in 2010.Known for his spontaneous hosting style, which has been characterized by The New York Times as "awkward, self-deprecating humor", O'Brien's late-night programs combine the "lewd and wacky with more elegant, narrative-driven short films". His segments outside the studio, dubbed "remotes", have also become some of his best-received work, including the international travel series Conan Without Borders. With the retirement of David Letterman on May 20, 2015, O'Brien became the longest-working late-night talk show host active in the United States. This active streak ended with O'Brien's retirement from late-night television in June 2021, with his entire run as a late-night host lasting almost 28 years.

Thomas Joseph Thyne (born March 7, 1975) is an American actor, best known for his role as Dr. Jack Hodgins in the television series Bones from 2005 to 2017.

David Chokachi (; born January 16, 1968) is an American film and television actor. He is known for his roles in the TV series Witchblade, Baywatch, and Beyond The Break.

Jack Evan Noseworthy Jr. is an American actor known for his roles in Event Horizon, U-571, Barb Wire, and Killing Kennedy.

Scott Andrew Evans (born September 21, 1983) is an American actor. He is known for playing the role of police officer Oliver Fish on the ABC daytime soap opera One Life to Live, the recurring role of Oliver on the series Grace and Frankie, and one of the Kens in Barbie. He is the younger brother of actor Chris Evans.

Nathan Harris Corddry (born September 8, 1977) is an American actor and comedian best known for his roles as Adam Branch on Harry's Law and for his role as Gabriel in the first two seasons of Mom. He has also guest starred on series such as Law & Order: Criminal Intent, The Daily Show, United States of Tara, 30 Rock, and New Girl. He also played Private First-Class Loudmouth in the HBO miniseries The Pacific and Tom Jeter in Studio 60 on the Sunset Strip. In 2019, Corddry played engineer Larry Wilson in the Apple TV+ original science fiction space drama series For All Mankind. In 2021, Corddry had a recurring role in the TV adaptation of Paper Girls playing Larry Radakowski.

Van Hansis (born Evan Vanfossen Hansis on September 25, 1981) is an American actor. Hansis portrayed the rich Luke Snyder on the CBS soap opera As the World Turns from December 14, 2005 until the show's final episode September 17, 2010. The son of long running characters on the series, Luke is known for a gay romantic storyline cited as one of the first in American daytime television.
Hansis has had guest roles on several television series and starred in the 2011 thriller film Occupant. In December 2012, he began playing the role of Thom in the dark comedy web series EastSiders. Hansis later played Jess Gibson in the 2013 horror film Devil May Call, and starred as Dusty in the 2015 film Kiss Me, Kill Me.
Hansis was nominated for a Daytime Emmy Award in 2007, 2008 and 2009 for his As the World Turns role, and was nominated again in 2016 for his role on EastSiders.

Joseph Anthony (born Joseph Deuster; May 24, 1912 – January 20, 1993) was an American playwright, actor, and director. He made his film acting debut in the 1934 film Hat, Coat, and Glove and his theatrical acting debut in a 1935 production of Mary of Scotland. On five occasions he was nominated for a Tony Award for Best Direction.

Jonathan Frederick Togo (born August 25, 1977) is an American actor, best known for his role in CSI: Miami as Ryan Wolfe.

James H. Harrington III, professionally known as Jay Harrington, (born November 15, 1971) is an American actor. He is known for his role as the title character in the ABC sitcom Better Off Ted in 2009–2010, and since 2017 as Sgt. David "Deacon" Kay in S.W.A.T.