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The Sapienza University of Rome (Italian: Sapienza – Università di Roma), formally the Università degli Studi di Roma "La Sapienza", abbreviated simply as Sapienza, is a public research university located in Rome, Italy. It was founded in 1303 and is as such one of the world's oldest universities, and with 122.000 students, it is the largest university in Europe by enrollment. Due to its size, funding, and numerous laboratories and libraries, Sapienza is a major education and research centre in Southern Europe. The University is located mainly in the Città Universitaria (University city), which covers 44 ha (110 acres) near the Tiburtina Station, with different campuses, libraries and laboratories in various locations in Rome.
Most of the Italian ruling class studied at Sapienza. The Sapienza has educated numerous notable alumni, including many Nobel laureates, Presidents of the European Parliament and European Commissioners, heads of several nations, notable religious figures, scientists and astronauts. In September 2018, it was included in the top 100 of the QS World University Rankings Graduate Employability Ranking and in 2022 and 2023 it was ranked the best Italian University according to ARWU. In 2018, 2019, 2021 and 2022 it ranked first in the world for classics and ancient history.