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The Sorby Research Institute was a research facility that operated in the UK during and immediately after the Second World War in Sheffield, England. The Institute mostly investigated questions of nutrition. This was an important consideration in wartime Britain, where food was in short supply. The experiments into deficiency of vitamin A and vitamin C were particularly notable. However, other kinds of medical research was also undertaken, such as research into the transmission of scabies.
The leading figures in the institute were Kenneth Mellanby and Hans Adolf Krebs. The volunteers were mainly conscientious objectors to military service. Some of the experiments were unpleasant, or even dangerous. The Institute closed in 1946, soon after the end of the war.